Abstract: Objective To investigate the distribution and characteristics of public health emergencies from 2004 to 2008 in Zhejiang province, provide evidence for the prevention and control of public health emergency.Methods Descriptive epidemiological analysis was conducted.Results A total of 1000 public health emergencies were reported to occur in Zhejiang province.Infectious disease epidemics constituted the major part of the public health emergencies (85.5%), followed by food poisoning events (7.0%).March to June was the period when public health emergency more frequently occurred, and schools were the major sites, the public health emergencies occurred there accounted for 74.4%, Conclusion It is necessary to establish and improve the predicting and warning system， strengthen the response support system and improve the public health emergency response system to prevent public health emergency effectively.